Die Wirksamkeit von Nicht-Opioid-Analgetika zur postoperativen Zahnschmerzen: Eine Meta-Analyse

CRD COMMENTARY:

The authors stated the review question clearly and conducted a reasonable review of the literature. The criteria for inclusion were reported in great detail and the included studies were listed in tabular format.
The authors limited their literature search to English language studies in only two databases and did not report whether they searched for unpublished data. It is unclear whether additional relevant studies may have been missed.
The authors did not state who selected the articles and extracted the data. In addition, it was not stated whether the selected articles were specifically reviewed for quality, although the selected studies were limited to randomised controlled trials with stated outcome measures and minimum follow-up periods. A random-effects model was used, but there was no test for homogeneity; this is important where there were many different treatment regimes and participant study characteristics in the meta-analysis.
The authors' conclusions have been reported selectively from the results. In the few cases where statistically-significant results were reported, these should be viewed with caution because the quality of the included studies was not assessed and there may have been bias in the study selection, review, data extraction and meta-analysis.