Broad Syntheses including this primary study

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Broad synthesis / Living FRISBEE

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Is antibiotic prophylaxis beneficial in acute pancreatitis?--First update.

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Authors Rada, Gabriel , Pena, Jose
Journal Medwave
Year 2015
Links Pubmed DOI

This article includes 18 Systematic reviews Systematic reviews (18 references) 19 Primary studies Primary studies (19 references)

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This Living FRISBEE (Living FRIendly Summary of the Body of Evidence using Epistemonikos) is an update of the summary published in August 2014, based on two systematic reviews appeared in January and February 2015. There is controversy about the effects of prophylactic antibiotics in acute pancreatitis. Searching in Epistemonikos database, which is maintained by screening 30 databases, we identified 18 systematic reviews including 19 randomised studies overall. We combined the evidence using meta-analysis and generated a summary of findings following the GRADE approach. We concluded that prophylactic antibiotics may reduce mortality and length of hospitalization in patients with acute pancreatitis, but the certainty of the evidence is low. The probability that future evidence change what we know is high.

Broad synthesis / Living FRISBEE

Unclassified

[Is antibiotic prophylaxis in acute pancreatitis beneficial?].

blocked
Authors Rada G , Peña J
Journal Medwave
Year 2014
Links Pubmed DOI

This article includes 18 Systematic reviews Systematic reviews (18 references) 19 Primary studies Primary studies (19 references)

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There is controversy about the effects of prophylactic antibiotics in acute pancreatitis. Searching in Epistemonikos database, which is maintained by screening 19 databases, we identified 15 systematic reviews including 19 randomised studies overall. We combined the evidence using meta-analysis and generated a summary of findings following the GRADE approach. We concluded that prophylactic antibiotics may reduce mortality and length of hospitalization in patients with acute pancreatitis, but the quality of the evidence is low. The probability that future evidence change what we know is high.