Cardiovascular risk of celecoxib in 6 randomized placebo-controlled trials: the Cross Trial Safety Analysis

Category Structured summary of systematic reviews
JournalDatabase of Abstracts of Reviews of Effects (DARE)
Year 2011
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CRD SUMMARY:

This review concluded that the risk of experiencing a cardiovascular event was greater with higher doses of celecoxib and with a greater underlying risk of such events. Despite some limitations in the review, the conclusion seems reliable for the populations evaluated in the trials, but might not be generalisable to populations treated with celecoxib on a long-term basis.
Epistemonikos ID: 34e369167d845e5f4014cfd1debf2fb0db3f465d
First added on: Jan 04, 2012