Broad Syntheses including this primary study

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Broad synthesis / Guideline

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Guidance for the use of medicinal cannabis in the treatment of palliative care patients in Australia

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Journal Therapeutic Goods Administration (TGA)
Year 2017
Links tga.gov.au

This article includes 3 Systematic reviews Systematic reviews (3 references) 16 Primary studies Primary studies (16 references)

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This document reflects the evidence supporting the use of medicinal cannabis in palliative care patients and the recommendations of the Palliative Care Working Group

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Cannabis: The Evidence for Medical Use

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Authors Barnes, MP , Barnes, JC
Report Group for Drug Policy Reform
Year 2016

This article includes 124 Primary studies Primary studies (124 references) 25 Systematic reviews Systematic reviews (25 references)

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Broad synthesis / Living FRISBEE

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Are cannabinoids effective for treatment of pain in patients with active cancer?

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Journal Medwave
Year 2016
Links Pubmed DOI

This article includes 9 Systematic reviews Systematic reviews (9 references) 7 Primary studies Primary studies (7 references)

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Cannabinoids have been proposed for the treatment of patients with cancer pain, especially if standard treatment does not control symptoms. Using Epistemonikos database, which is maintained by searching 30 databases, we identified nine systematic reviews including seven trials that answer the question of interest, of which six are randomized trials. We performed a meta-analysis and generated a summary of findings table using the GRADE approach. We concluded it is unclear whether cannabinoids decrease pain and improve quality of life in patients with refractory cancer pain because the certainty of the evidence is very low, and it probably increases adverse effects substantially.