Cannabinoids for the Treatment of Chronic Non-Cancer Pain: An Updated Systematic Review of Randomized Controlled Trials

Authors
Category Systematic review
JournalJournal of Neuroimmune Pharmacology
Year 2015

This article is included in 5 Broad syntheses 11 Broad syntheses (5 references)

This article includes 11 Primary studies 11 Primary studies (11 references)

This article is part of the following publication threads:
  • Lynch et al [Systematic review: Cannabinoids for Chronic Non-Cancer Pain] (2 documents)
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An updated systematic review of randomized controlled trials examining cannabinoids in the treatment of chronic non-cancer pain was conducted according to PRISMA guidelines for systematic reviews reporting on health care outcomes. Eleven trials published since our last review met inclusion criteria. The quality of the trials was excellent. Seven of the trials demonstrated a significant analgesic effect. Several trials also demonstrated improvement in secondary outcomes (e.g., sleep, muscle stiffness and spasticity). Adverse effects most frequently reported such as fatigue and dizziness were mild to moderate in severity and generally well tolerated. This review adds further support that currently available cannabinoids are safe, modestly effective analgesics that provide a reasonable therapeutic option in the management of chronic non-cancer pain.
Epistemonikos ID: 8b03c88cc1f47cc4e91c3ef41c079720065bf774
First added on: May 04, 2015