Systematic reviews including this primary study

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Systematic review

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Complementary and alternative medicine in fibromyalgia and related syndromes

Journal Best practice & research. Clinical rheumatology
Year 2003
Links Pubmed DOI

This article is included in 1 Structured summary of systematic reviews 22 Structured summaries of systematic reviews (1 reference) 3 Broad syntheses 22 Broad syntheses (3 references)

This article includes 22 Primary studies 22 Primary studies (22 references)

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Complementary and alternative medicine (CAM) has gained increasing popularity, particularly among individuals with fibromyalgia syndrome (FMS) for which traditional medicine has generally been ineffective. A systematic review of randomized controlled trials (RCTs) and non-RCTs on CAM studies for FMS was conducted to evaluate the empirical evidence for their effectiveness. Few RCTs achieved high scores on the CONSORT, a standardized evaluation of the quality of methodology reporting. Acupuncture, some herbal and nutritional supplements (magnesium, SAMe) and massage therapy have the best evidence for effectiveness with FMS. Other CAM therapies have either been evaluated in only one RCT with positive results (Chlorella, biofeedback, relaxation), in multiple RCTs with mixed results (magnet therapies), or have positive results from studies with methodological flaws (homeopathy, botanical oils, balneotherapy, anthocyanidins, dietary modifications). Lastly, other CAM therapies have neither well-designed studies nor positive results and are not currently recommended for FMS treatment (chiropractic care). © 2003 Elsevier Science Ltd. All rights reserved.

Systematic review

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A meta-analysis of fibromyalgia treatment interventions.

Journal Annals of behavioral medicine : a publication of the Society of Behavioral Medicine
Year 1999
Links Pubmed DOI www.epistemonikos.org

This article is included in 1 Structured summary of systematic reviews 48 Structured summaries of systematic reviews (1 reference) 1 Broad synthesis 48 Broad syntheses (1 reference)

This article includes 48 Primary studies 48 Primary studies (48 references)

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OBJECTIVE: To evaluate and compare the efficacy of pharmacological and nonpharmacological treatments of fibromyalgia syndrome (FMS). METHODS: This meta-analysis of 49 fibromyalgia treatment outcome studies assessed the efficacy of pharmacological and nonpharmacological treatment across four types of outcome measures-physical status, self-report of FMS symptoms, psychological status, and daily functioning. RESULTS: After controlling for study design, antidepressants resulted in improvements on physical status and self-report of FMS symptoms. All nonpharmacological treatments were associated with significant improvements in all four categories of outcome measures with the exception that physically-based treatment (primarily exercise) did not significantly improve daily functioning. When compared, nonpharmacological treatment appears to be more efficacious in improving self-report of FMS symptoms than pharmacological treatment alone. A similar trend was suggested for functional measures. CONCLUSION: The optimal intervention for FMS would include nonpharmacological treatments, specifically exercise and cognitive-behavioral therapy, in addition to appropriate medication management as needed for sleep and pain symptoms.