Primary studies included in this systematic review

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36 articles (37 References) Revert Studify

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The National Children Study (NCS) ist geplant, die größte Langzeitstudie des Umwelt und genetischen Effekten auf die Gesundheit der Kinder jemals in den Vereinigten Staaten durchgeführt werden. Sie schlägt vor, die Auswirkungen von Umwelteinflüssen auf die Gesundheit und Entwicklung von rund 100.000 Kinder in den Vereinigten Staaten, zu untersuchen von vor der Geburt nach, bis 21 Jahren. NICHD forderte den Ausschuss für nationale Statistik des National Research Council (NRC), in Zusammenarbeit mit dem Vorstand über Kinder, Jugend und Familie des NRC und des Institute of Medicine (IOM) und der IOM Foren für Bevölkerung Gesundheit und Public Health-Praxis , um eine Überprüfung der Forschungsplan für das NCS durch. Ziel der Überprüfung ist es, die wissenschaftliche Strenge des NCS und beurteilen, inwieweit es wird mit Methoden, Maßnahmen und Sammlung von Daten und Proben durchgeführt, um die wissenschaftliche Ausbeute der Studie zu maximieren. Zu behandelnden Themen umfassen vorgeschlagenen Ergebnisse und Hypothesen werden; vorgeschlagenen Maßnahmen der Umweltexposition, genetische Veranlagung, Familie und Gemeinschaft Umwelt und persönlichen Eigenschaften; vorgeschlagenen Datenerfassung und Analysemethoden; und andere Aspekte der Studie Forschungsplan.

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Cohort profile: the Amsterdam Born Children and their Development (ABCD) study.

Journal International journal of epidemiology
Year 2011
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Developing and refining the Taiwan Birth Cohort Study (TBCS): five years of experience.

Authors Lung FW , Chiang TL , Lin SJ , Shu BC , Lee MC
Journal Research in developmental disabilities
Year 2011
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The Taiwan Birth Cohort Study (TBCS) is the first nationwide birth cohort database in Asia designed to establish national norms of children's development. Several challenges during database development and data analysis were identified. Challenges include sampling methods, instrument development and statistical approach to missing data. The purpose of this paper is to describe the pilot study underpinning the TBCS, testing of the TBCS developmental instrument and the resolution of methodological challenges. Bayesian analysis fill in missing data, three-step regression analysis for the investigation of mediating and moderating effect, the use of structural equation modeling in a large scale investigation, investigating direct and indirect effects, confounding factors and reciprocal relationships in children's development, and used latent growth model in longitudinal observations are described. The TBCS will provide ongoing longitudinal information regarding the predisposing and maintaining factors affecting the long term outcome of pediatric illnesses.

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National Children's Study: update in 2010.

Journal The Mount Sinai journal of medicine, New York
Year 2011
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The National Children's Study will examine the effects of the environment and genetics on the growth, development, and health of children across the United States; it will follow participants from before birth until age 21 years. The goal of the study is to improve the health and well-being of children and contribute to understanding the roles various factors play in health and disease. Findings from the study will be made available as the research progresses, making potential benefits known to the public as soon as possible. A robust pilot study, or Vanguard Study, is underway to generate data for designing the subsequent Main Study. The goals of the Vanguard Study are feasibility, acceptability, and cost, and the goals of the Main Study will be exposure-response relationships and biological, environmental, and genetic interactions. The initial Vanguard Study experience among 7 study centers was successful in many ways, including delineating the topics to explore for the next phase of the Vanguard Study. Three different recruitment strategies are under evaluation to determine what approach to use for the Main Study. The organization of National Children's Study operations is currently based on a new decentralized business model.

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Cohort profile: the Jamaican 1986 birth cohort study.

Journal International journal of epidemiology
Year 2011
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This article is included in 1 Systematic review Systematic reviews (1 reference)

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Cohort profile: the Cebu longitudinal health and nutrition survey.

Journal International journal of epidemiology
Year 2011
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This article is included in 1 Systematic review Systematic reviews (1 reference)

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Factors in infancy and childhood related to reduced lung function in asthmatic children: a birth cohort study (BAMSE).

Journal Pediatric pulmonology
Year 2010
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This article is included in 1 Systematic review Systematic reviews (1 reference)

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Changes in lung function due to childhood asthma have been reported to occur before school age, and to persist throughout life. The aim was to assess the relationship between aspects of lung function and asthma over time in 4,089 children participating in the large population-based birth cohort BAMSE. Questionnaires were administered at 1, 2, 4, and 8 years of age. At 4 and 8 years, children were invited to a clinical examination, in which 2,965 and 2,630 children participated, respectively. The examinations included blood sampling for evaluation of sensitization to airway allergens (n = 2,053), peak expiratory flow (PEF) measurements at 4 and 8 years (n = 1,957), and forced expiratory flows (n = 2,455) at 8 years. Asthma onset before the age of 4 years, but no thereafter, was at 8 years associated with impaired spirometric flows. This was seen irrespective of symptom presence after the age of 4. Reduced PEF growth between the age of 4 and 8 was seen only for the group of children with early onset transient asthma, while an association between sensitization and lung function was only seen in the late-onset asthma group. In conclusion, school children with asthma have reductions of spirometric flows when categorized as persistent or transient early onset asthma, even if this latter group of children is completely symptom-free at school age.

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Unclassified

The prevalence of SDQ-measured mental health problems at age 5-7 years and identification of predictors from birth to preschool age in a Danish birth cohort: the Copenhagen Child Cohort 2000.

Journal European child & adolescent psychiatry
Year 2010
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This article is included in 1 Systematic review Systematic reviews (1 reference)

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The objective of the study is to investigate the prevalence, distribution and predictors of mental health problems in 5-7-year-old Danish children in the general population. This study is a 5-7-year follow-up study of a birth cohort of 6,090 children, the Copenhagen Child Cohort 2000. The extended version of the Strengths and Difficulties Questionnaire (SDQ) was answered by parents and pre-school teachers. Data from Danish national registers included perinatal data, socioeconomic data and data on child mental illness diagnosed at hospital in preschool age. Register data from the first year of life was obtained from 99.7% of the children in the cohort. Of 5,898 eligible children, 3,501 participated in the SDQ assessment (59%). The overall estimated 6-month prevalence of mental health problems was 4.8% (95% CI 4.1-5.6). Conduct problems were found in 3.0% (95% CI 2.4-3.6), problems of hyperactivity/inattention in 0.7% (95% CI 0.4-1.0) and emotional problems in 1.5% (95% CI 1.1-1.9). Boys showed a higher risk of having mental health problems as compared to girls: risk ratio 2.0 (95% CI 1.5-2.8). Several markers of socioeconomic disadvantages were associated with mental health problems at 5-7 years of age. In conclusion, the 6-month prevalence of SDQ-measured mental health problems was relatively low in Danish children when compared with findings from several European countries, but was in line with findings from other studies in Nordic countries. The lower prevalence might reflect differences in psychosocial risk load and environmental stress given the social and cultural context.

Primary study

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Saving the National Children's Study.

Authors Savitz DA , Ness RB
Journal Epidemiology (Cambridge, Mass.)
Year 2010
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This article is included in 1 Systematic review Systematic reviews (1 reference)

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Adolescent manifestations of metabolic syndrome among children born to women with gestational diabetes in a general-population birth cohort.

Journal American journal of epidemiology
Year 2009
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This article is included in 1 Systematic review Systematic reviews (1 reference)

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The association between maternal gestational diabetes (GDM) and manifestations of metabolic syndrome among Caucasian adolescents was studied with data from the population-based Northern Finland 1986 Birth Cohort. This is a longitudinal cohort study from early pregnancy until offspring age 16 years and includes data from a risk group-based GDM screen of pregnant mothers by an oral glucose tolerance test. Metabolic outcomes were compared between the offspring of women with GDM (OGDM; n = 95) and reference group offspring (n = 3,909). The prevalence of overweight was significantly higher in the OGDM group (18.8 vs. 8.4%; P < 0.001) than in the reference group. The median body mass index (20.8 vs. 20.2 kg/m(2), 95% confidence interval (CI) for the percentage difference adjusted for sex: 3.5%, 9.5%), waist circumference (73.3 vs. 71.5 cm, 95% CI: 3.2%, 7.5%), and fasting insulin (10.20 vs. 9.30 milliunits/L, 95% CI: 5.9%, 26.0%) were higher, and homeostatic model assessment-insulin sensitivity (74.7 vs. 82.3, 95% CI: -20.6%, -5.4%) was lower in the OGDM group. These differences were similar after an additional adjustment for birth weight and gestational age. The differences in waist circumference, insulin, and homeostatic model assessment-insulin sensitivity were attenuated but remained statistically significant after additional adjustment for body mass index at 16 years. These findings highlight the importance of prevention strategies among children born to women with GDM.