Effect of a nitrogen analog of tetrahydrocannabinol on cancer pain.

Authors
Category Primary study
JournalClinical pharmacology and therapeutics
Year 1978
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Two consecutive, randomized, double-blind trials were performed to test the analgesic properties of a synthetic nitrogen analog of tetrahydrocannabinol (NIB). In the first trial, the test preparation was superior to placebo and approximately equivalent to 50 mg of codeine phosphate. In the second study, the tetrahydrocannabinol analog was superior to placebo and to 50 mg secobarbital. NIB is not useful clinically because of the frequency of side effects.
Epistemonikos ID: aaa9a04fa609d3098484f2a18f1ff3fe70525750
First added on: May 15, 2012