Novel coronavirus sars? CoV? 2 Journal of Genetic Testing and Its Imaging Controls %J Molecular Diagnosis and Therapy

Objective To study novel coronavirus (SARS? CoV? 2) Nucleic acid gene detection and its imaging control. method of real-time fluorescence RT? PCR method detecting SARS? CoV? 2 orf1a/b and N genes, analyzed 23 cases of SARS? CoV? 2 Clinical and imaging data of patients with positive nucleic acid. Results ① 3 cases of asymptomatic infections, COVID? 19 confirmed 20 cases, 2 to 24 days incubation period, 5 cases of adult light, 1 case of child light, 1 case of young person, 13 cases of adult general type. CoV? 2 genetically positive patients, sputum specimens have higher viral content and detection effects than nasopharyngeal swabs specimens, N gene feces longer than phlegm and nasopharyngeal swab positive duration. 30.0% (6/20) CT scans did not see abnormalities. Viral load and imaging correspond unproportionally to peripheral band (13/14) and posterior basal segment of the lower lobe (11/14), involvement of two or more pulmonary lobes (11/14), bilateral lesions (11/14) .14 CT abnormal COVID? In 19, imaging is mainly shown by gross glass shadow (10/14), double lung flake shadow (10/14), halo sign (8/14), fine mesh sign (5/14), and thickening with lobe intervals (5/14), bronchial inflatable signs (5/14), and small vascular thickening (5/14). Relationship, sars? CoV? 2 Nucleic acid detection combined with CT scan, epidemiological history can improve COVID? 19, can not be relied on solely on nucleic acid PCR or CT tests.