To Compare the Outcome, Complications and Management of Complications of Trabeculectomy with Ologen Implant Versus Trabeculectomy with MMC

Trabeculectomy was introduced as far back as 1968 and is now the most common operation for the treatment of glaucoma worldwide.1,2 However, wound healing and scar formation may result in fibrosis of the bleb and obstruction of the drainage fistula, eventually leading to bleb failure.4 Hence, the inhibition of scar formation during the wound-healing process should promote greater success. Ologen Collagen Matrix is an artificial extracellular matrix (ECM) specifically configured to support repair in connective and epithelial ocular tissue. The implantation of this bioengineered, biodegradable, porous collagenglycoaminoglycan matrix implant in the subconjunctival space offers an alternative method for controlling the wound-healing process following filtration surgery, avoiding the complications of the administration of antifibrotic agents and offering the potential for maintaining long-term intraocular pressure (IOP) control.5,6 The purpose of this study was to compare the outcomes of trabeculectomy with OloGen implant and trabeculectomy with MMC in patients requiring glaucoma surgery for uncontrolled IOP. Other outcomes measured were the number of postoperative medications used and any complications.