Living Systematic Review on Cannabis and Other Plant-Based Treatments for Chronic Pain: Interim Progress Reports

This is the first progress report for an ongoing living systematic review on plant-based treatments for chronic pain. The systematic review will synthesize evidence on the benefits and harms of plant-based compounds (PBCs) such as cannabinoids and kratom used to treat chronic pain, addressing concerns about severe adverse effects, abuse, misuse, dependence, and addiction. The purpose of this progress report is to describe the body of literature identified thus far. This report will be periodically updated with new studies as they are published and identified, culminating in a systematic review that provides a synthesis of the accumulated evidence.