What are the effects of hypertonic saline plus furosemide in acute heart failure?

Authors
Category Broad synthesis / Living FRISBEE
JournalMedwave
Year 2015
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In search of new therapies to solve diuretic resistance in acute heart failure, the addition of hypertonic saline has been proposed. Searching in Epistemonikos database, which is maintained by screening 30 databases, we identified two systematic reviews including nine pertinent randomized controlled trials. We combined the evidence and generated a summary of findings following the GRADE approach. We concluded hypertonic saline associated with furosemide probably decrease mortality, length of hospital stay and hospital readmission in patients with acute decompensated heart failure.
Epistemonikos ID: 43c888de4724ee28f54dd4bffe86051b14dae6e9
First added on: Aug 04, 2017