Primary study

Unclassified

Bioavailability of beetroot compounds in older adults

Year 2017
Authors Capper, Tess , Stevenson, Emma
Registry of Trials ISRCTN registry
Links DOI , ISRCTN

This article is not included in any systematic review

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INTERVENTION:

Participants are randomised using a Latin‐Square method. Participants are allocated in a random order to receive the four interventions. The four interventions include: 1. 100g whole pre‐cooked beetroot 2. 200g whole pre‐cooked beetroot 3. 300g whole pre‐cooked beetroot 4. 200ml potassium nitrate solution. Participants are asked to consume the supplement within 15 minutes after baseline testing, and measurements will be taken for 5 hours post‐supplementation. The duration of each intervention will be five hours. The washout period between each phase will be one week.

CONDITION:

Age‐related degenerative diseases ; Nutritional, Metabolic, Endocrine ; Age‐related degenerative diseases

PRIMARY OUTCOME:

Differences in bioavailability of nitrate between incremental doses of beetroot and compared to a standard dose of potassium nitrate at five hours.

SECONDARY OUTCOME:

1. Differences in changes in blood pressure following each dose of nitrate supplementation and compared to a standard dose of potassium nitrate at five hours; 2. Differences in changes in endothelial function following each dose of nitrate supplementation and compared to a standard dose of potassium nitrate at five hours; 3. Differences in changes in exhaled nitric oxide following each dose of nitrate supplementation and compared to a standard dose of potassium nitrate at five hours; 4. Differences in bioavailability of betalains and phenolic compounds between incremental doses of beetroot and compared to a standard dose of potassium nitrate at five hours;

INCLUSION CRITERIA:

1. Non‐obese 2. Non‐smoker 3. Males aged between 18 and 35 or 60 and 75 4. Free of chronic illness

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Primary study

Unclassified

Beetroot Supplementation and High Intensity Exercise

Year 2023
Registry of Trials ClinicalTrials.gov
Links ClinicalTrials.gov

This article is not included in any systematic review

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Ingested beetroot contains inorganic nitrate which is later converted to nitric oxide (NO) in the bloodstream. NO is an important signaling molecule with several physiological functions in the body including acting as a vasodilator, expanding arteries and improving blood flow. Beetroot juice contain inorganic nitrate and consumption of beetroot has been shown to improve skeletal muscle contractility and metabolism enhancing high-intensity exercise performance. Isotonic sports drinks contain carbohydrates and sodium, which also improve exercise performance by providing exogenous glucose for energy to the working muscle and central nervous system and enabling faster absorption of fluid into the bloodstream. The ingestion of exogenous nitrate and isotonic-carbohydrate drink are recognized strategies for promoting exercise performance but whether they can be effectively combined has not been shown. This study will compare the salivary nitrite response, muscle oxygenation and time-trial performance after ingestion of two isotonic drinks with high in nitrate or with no nitrate.

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Primary study

Unclassified

Beetroot Juice and Endothelial function in Men

Year 2014
Authors [No authors listed]
Registry of Trials Netherlands Trial Register
Links

This article is not included in any systematic review

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INTERVENTION:

Beetroot juice

CONDITION:

Endothelial function ; ;

PRIMARY OUTCOME:

Degree of correlation between FMD and

LTH SECONDARY OUTCOME:

• Involvement of NO in LTH response ; ; • Changes in FMD and LTH in response to beetroot juice consumption. ;

INCLUSION CRITERIA:

Non‐smokers: ‐ Healthy Men ‐ Age between 25‐65 years ‐ Non‐smoking for > 5 years ‐ Body mass index between 18 and 30 kg/m2 ‐ Capable and willing to give informed consent ‐ General good health, based on medical history and physical examination ‐ Systolic BP measured on day of the experiment should be < 160 mmHg Smokers: ‐ As for the non‐smokers ‐ In addition smoking at least on average 14 cigarettes per day for at least 5 years

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Primary study

Unclassified

Beetroot Juice Supplementation in Basketball Players

Year 2019
Authors Universidad de Murcia
Registry of Trials clinicaltrials.gov
Links ClinicalTrials.gov

This article is not included in any systematic review

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Whereas beetroot juice (BJ) supplementation is shown to increase physical performance in endurance activities, its benefits in team sports has been barely studied. In this randomized placebo-controlled study, we investigated the effects of BJ acute supplementation in improving neuromuscular performance and physical match activity in basketball.

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Primary study

Unclassified

Beetroot Juice Doses and Anaerobic Performance

Year 2016
Authors University of Manitoba
Registry of Trials clinicaltrials.gov
Links ClinicalTrials.gov

This article is not included in any systematic review

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The purpose of this study is to examine the effect of varying nitrate doses of beetroot juice supplementation on dynamic, multijoint resistance exercise performance in active, trained individuals. Performance will be assessed based on parameters including neuromuscular efficiency, anaerobic performance capability, oxygen consumption, plasma nitrate/nitrite levels, specific muscle tissue biomarkers including lactate, and anthropometric measurements of select muscle groups.

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Primary study

Unclassified

Effect of beetroot juice ingestion on strength

Year 2024
Registry of Trials Brazilian Registry of Clinical Trials
Links ReBEC

This article is not included in any systematic review

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Primary study

Unclassified

Beetroot Juice and Postprandial Vascular Activity

Year 2012
Registry of Trials clinicaltrials.gov
Links ClinicalTrials.gov

This article is not included in any systematic review

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Increased postprandial lipemia may increase the risk for cardiovascular diseases. An important mechanistic link between lipemia following a high-fat meal and adverse cardiovascular events is lipid-mediated endothelial activation. Therefore, it is important to identify nutrients that can neutralize this acute vascular disturbance.

The investigators hypothesize that beetroot juice, a food rich in inorganic nitrate, could improve vascular activity during the postprandial phase.

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Primary study

Unclassified

Beetroot juice lowers blood pressure

Year 2012
Registry of Trials ANZCTR
Links ANZCTR

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INTERVENTION:

The study was designed as a randomised, placebo controlled cross‐over study with a 2 week washout period. Volunteers consumed a single dose of 500g of Sunraysia Beetroot and Apple Juice in the institute clinic over 5 ‐ 10 minutes. Systolic / diastolic blood pressure and pulse rate was then monitored over the following 24 hours using an ambulatory blood pressure monitor. Volunteers were asked to avoid moderate or vigorous physical activity on the day of the trial, but no other restrictions, such as diet, were required of volunteers, either on intervention days or during the washout period.

CONDITION:

Hypertension

PRIMARY OUTCOME:

Change in diastolic blood pressure relative to control using an ambulatory blood pressure monitor. Change in systolic blood pressure relative to control using an ambulatory blood pressure monitor.

SECONDARY OUTCOME:

Change in pulse pressure relative to control using an ambulatory blood pressure monitor.

INCLUSION CRITERIA:

Resting baseline systolic blood pressure greater than 120 mmHg on first day of treatment. No upper limit on systolic blood pressure ‐ hypertensive subjects also eligible

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Primary study

Unclassified

Effects of Beetroot Juice in Postmenopausal and Hypertensive

Year 2018
Registry of Trials clinicaltrials.gov
Links ClinicalTrials.gov

This article is not included in any systematic review

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The intervention protocol will last 3 days. On the first day there will be the collection of anthropometric data, the signature of a consent term and delivery of the list of foods that should be avoided 24 hours before the tests and a treadmill familiarization. On the second and third day the physical intervention will be performed associated with juice or placebo supplementation. A wash out period of at least 7 days will be performed between the second and third day. The volunteers will arrive at the laboratory at 7am in the fasted state and will be rested until 07:20am and then the blood pressure (BP) measurement (collected three times, with an interval of 1 minute between measurements), collection of the saliva and the measurement of heart rate (HR). Approximately at 07:30am they will start drinking the juice and will have up to 15 minutes to consume. BP will be measured at 08:00am, 08:30am, 09:00am and 09:30am. At 9:30am a physical exercise session will begin, during which will be monitored by a cardio‐frequency monitor, which will remain until 11h10am (period referring to the end of BP monitoring in the laboratory). At 10:10am the workout will be finished, and then the saliva will be collected. After this period, the volunteers can take up to 250 ml of water until 11:10am, and every 15 minutes, BP will also be measured. and at 11:10am a collection of saliva will be performed. The volunteers will have the period of 15 minutes to be hygienised, and at 11:25am the ABPM will be placed (ambulatory blood pressure monitor). The ABPM will be taken the day after the test at 10:10 am (time for the first post‐exercise BP measurement), and the last collection of saliva will be carried out concurrently with the ABPM removal.

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Primary study

Unclassified

Beetroot Juice and Endothelial function in Men

Year 2014
Authors Erasmus MC, Rotterdam
Registry of Trials Overview of Medical Research in the Netherlands
Links OMON

This article is not included in any systematic review

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