Primary studies included in this systematic review

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Primary study

Unclassified

Canada Vigilance Adverse Reaction Database

Autores Health Canada
Revista Available at: http://www.hc-sc.gc.ca/dhp-mps/ medeff/databasdon/index-eng.php. Updated November 16, 2010; Accessed on February 9, 2011
Year

Este artigo é incluído no 1 Systematic review Systematic reviews (1 reference)

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Primary study

Unclassified

FDA cites toxic risk of popular head-lice drug

Autores Appleby J
Revista USA Today
Year 2008

Este artigo é incluído no 1 Systematic review Systematic reviews (1 reference)

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Primary study

Unclassified

Fatality after a single dermal application of lindane lotion.

Autores Sudakin DL
Revista Archives of environmental & occupational health
Year 2007
Links Pubmed DOI

Este artigo é incluído no 1 Systematic review Systematic reviews (1 reference)

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Lindane lotion, approved by the US Food and Drug Administration (FDA) for treatment of scabies and lice, poses risks of serious adverse effects on the nervous system. In 2003, the FDA issued a public health advisory for lindane products, emphasizing the importance of compliance with labeling instructions. The author presents a case in which a fatal outcome followed a single dermal application of lindane. The product was not applied according to the labeling instructions, and the 66-year-old man rapidly developed hypoxemia, seizures, respiratory acidosis, and hypotension. The final diagnosis at autopsy was hypoxic ischemic encephalopathy from lindane. This case is consistent with other reports of severe neurological outcomes from pharmaceutical use of lindane. These factors suggest a need for the FDA to reassess whether the risks of lindane have been effectively communicated to healthcare providers.

Primary study

Unclassified

Acute generalized exanthematous pustulosis induced by topical lindane.

Autores Juan WH , Yang LC , Hong HS
Revista Dermatology (Basel, Switzerland)
Year 2004
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Este artigo é incluído no 1 Systematic review Systematic reviews (1 reference)

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Primary study

Unclassified

Lindane lotion, USP, 1% prescribing information

Autores FDA
Revista http://www. accessdata.fda.gov/drugsatfda_docs/label/2003/006309lot ionlbl.pdf
Year 2003

Este artigo é incluído no 1 Systematic review Systematic reviews (1 reference)

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Primary study

Unclassified

Lindane Assessment Memorandum

Revista
Year 2003

Este artigo é incluído no 1 Systematic review Systematic reviews (1 reference)

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Primary study

Unclassified

Acute lindane poisoning in three children

Autores Nordt SP , Chew G
Revista J Emerg Med
Year 2000

Este artigo é incluído no 1 Systematic review Systematic reviews (1 reference)

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Primary study

Unclassified

Long-term psychological and neurological complications of lindane poisoning.

Autores Hall RC , Hall RC
Revista Psychosomatics
Year 1999
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Este artigo é incluído no 1 Systematic review Systematic reviews (1 reference)

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A thin, healthy, partial-vegetarian, white female, who was exposed to three doses of lindane (through the application of Kwell), developed a severe case of long-term lindane poisoning. Review of the literature suggests that her toxicity was so severe because of the repetitive nature of her exposure and the fact that she was partly protein restricted when first exposed. She developed profound central nervous system toxicity, as well as skin and gastrointestinal changes, that persisted for 20 months. She was treated with high doses of Valium. It was noted that every time her Valium was diminished below a critical level, her symptoms tended to recur until she had adequately cleared the lindane from her system. We believe this is the longest term of poisoning reported following exposure to an organochloride insecticide. Her symptoms are well explained by the physiology of these compounds as described in the literature. The case is important, for it represents the longest persistence of symptoms clearly associated with poisoning by the potent gamma isomer of BHC-lindane.

Primary study

Unclassified

Acute accidental lindane ingestion in toddlers.

Revista Annals of emergency medicine
Year 1995
Links Pubmed

Este artigo é incluído no 1 Systematic review Systematic reviews (1 reference)

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Lindane toxicity has been reported to occur mostly by way of dermal exposure. Cases of ingestion in which blood levels have been determined are rare. We present three such cases, along with a comparison of cases in the literature with respect to blood level half-lives and correlation with signs of toxicity. Emergency physicians can prevent acute ingestion by educating patients on the proper use of lindane and by selecting less toxic scabicidal agents.

Primary study

Unclassified

Lindane toxicity in a 24-year-old woman

Autores Fischer TF
Revista Ann Emerg Med
Year 1994

Este artigo é incluído no 1 Systematic review Systematic reviews (1 reference)

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