Primary studies included in this systematic review

loading
6 articles (6 References) loading Revert Studify

Primary study

Unclassified

Repetitive transcranial magnetic stimulation improve tinnitus in normal hearing patients: A double-blind controlled, clinical and neuroimaging outcome study

期刊 European journal of neurology
Year 2010
連結 Pubmed DOI

此文章收錄於 1 Systematic review Systematic reviews (1 reference)

Loading references information
Background and purpose: Tinnitus is a frequent disorder which is very difficult to treat and there is compelling evidence that tinnitus is associated with functional alterations in the central nervous system. Targeted modulation of tinnitus-related cortical activity has been proposed as a promising new treatment approach. We aimed to investigate both immediate and long-term effects of low frequency (1 Hz) repetitive transcranial magnetic stimulation (rTMS) in patients with tinnitus and normal hearing. Methods: Using a parallel design, 20 patients were randomized to receive either active or placebo stimulation over the left temporoparietal cortex for five consecutive days. Treatment results were assessed by using the Tinnitus Handicap Inventory. Ethyl cysteinate dimmer-single photon emission computed tomography (SPECT) imaging was performed before and 14 days after rTMS. Results: After active rTMS there was significant improvement of the tinnitus score as compared to sham rTMS for up to 6 months after stimulation. SPECT measurements demonstrated a reduction of metabolic activity in the inferior left temporal lobe after active rTMS. Conclusion: These results support the potential of rTMS as a new therapeutic tool for the treatment of chronic tinnitus, by demonstrating a significant reduction of tinnitus complaints over a period of at least 6 months and significant reduction of neural activity in the inferior temporal cortex, despite the stimulation applied on the superior temporal cortex. © 2009 EFNS.

Primary study

Unclassified

重复经颅磁刺激治疗难治性慢性耳鸣：一项随机，安慰剂对照研究的疗效。

automatic
期刊 Neuro endocrinology letters
Year 2010
連結 Pubmed

此文章收錄於 1 Systematic review Systematic reviews (1 reference)

Loading references information
目的：特发性耳鸣的病理生理机制尚不清楚。在听觉皮层低频rTMS的应用已经提出了异常，增加皮质活动，包括在听觉皮层的活动增加耳鸣的病理条件下的新的和因果关系导向治疗方法。然而现有的研究是一个积极的报告上重复经颅磁刺激治疗耳鸣（RTMS）的治疗效果的特点，也有具体的治疗效果的持续时间有关的一些细节。 设计：本研究设计是随机，前瞻性，安慰剂对照。右手的患者用真实或假1赫兹以上频率的rTMS的为期两周的。52例与慢性，治疗耐药性耳鸣和稳定的药物被纳入研究，给予书面知情同意书后，42例完成了研究和数据分析。 结果：在两个随机组的能力，以减少耳鸣的症状出现后立即1 Hz的rTMS的假刺激相。耳鸣耳鸣残疾量表（骅）的总比分两组有一个显着减少（真正rTMS的P = 0.005;假rTMS的供磷= 0.049）和耳鸣问卷（TQ）的总成绩（实际rTMS的供磷= 0.003;假RTMS P = 0.049）。骅评价尺度上，在真正的rTMS的温和恶化注意到在第2周达到国家相比，在6周。在随后的研究过程中坚持的总得分显着减少的情况骅（真正rTMS的第14周P = 0.033和边缘一周26 P = 0.058）。显著减少的症状，作为评价使用的天晴相比，在真正rTMS治疗组基线在第2周，6日和14（P = 0.003，P = 0.024，P = 0.022）。仅在第2周（P = 0.049）达到治疗组与假刺激症状显着减少。在关系到以百分比表示的基准后续的总得分记录值的差异比较说明的由两个基本尺度评估在RTMS和假刺激的效果差异。平均治疗的反应，根据刺激型模式的图形分析显示治疗反应的评估模式，减少使用骅和TQ总分之间的相似性。 结论：本研究的主要发现是，真正的1 Hz的rTMS的治疗能够显着降低总基线得分的基本尺度，耳鸣措施的严重性。这个结果是很重要的，因为它证明，症状显着减少，甚至可以在一组抗药物治疗长期症状的患者。

Primary study

Unclassified

不同的刺激频率比较：每天重复经颅磁刺激治疗耳鸣的效果。

automatic
期刊 Journal of neurology, neurosurgery, and psychiatry
Year 2008
連結 Pubmed DOI

此文章收錄於 1 Systematic review Systematic reviews (1 reference)

Loading references information
我们对66例慢性乙型肝炎患者的效果比较不同频率的重复经颅磁刺激（rTMS）（1赫兹，10赫兹，25赫兹和假（枕，1赫兹）），2周，每天在左颞皮层耳鸣随机分为四组。每月此后连续4个月2周的治疗和患者耳鸣盘口库存，自评症状和抑制残余听力的措施之前，使用后立即进行了评估。结果：有四组患者之间没有显着差异，在基础措施。双因素方差分析显示，1显著“rTMS的”X“时间”的所有措施的相互作用。这是因为真正的rTMS的产生更大的改善比假。然而，有不同频率的rTMS的反应之间没有显着差异。 rTMS的反应取决于耳鸣持续时间：患者有耳鸣的时间最长的人最有可能对治疗产生反应。结论：在颞皮层rTMS的每日会议可能会成为一个有用的治疗耳鸣的潜力。

Primary study

Unclassified

High-frequency pulsed electromagnetic energy in tinnitus treatment.

期刊 The Laryngoscope
Year 2004
連結 Pubmed DOI

此文章收錄於 1 Systematic review Systematic reviews (1 reference)

Loading references information
OBJECTIVES/HYPOTHESIS: Electromagnetic therapy has been used with reported success in multiple clinical settings, including the treatment of seizure disorders, brain edema, migraine headaches, revascularization of burn wounds, and diabetic ulcers. The purpose of the study was to investigate the effect of pulsed high-frequency electromagnetic therapy on chronic tinnitus. STUDY DESIGN: A randomized, prospective, double-blind, placebo-controlled pilot study was conducted to evaluate the effectiveness of high-frequency pulsed electromagnetic energy using the Diapulse device in the treatment of chronic tinnitus. Thirty-seven adult patients with chronic tinnitus of at least 6 months' duration were recruited and randomly assigned to either a treatment or a placebo group. METHODS: Patients received 30-minute treatments with the Diapulse device three times a week for 1 month. The unit was set to deliver electromagnetic energy at a frequency of 27.12 MHz at a repetition rate of 600 pulses per second. All subjects had pretreatment and post-treatment audiological testing, including tinnitus frequency and intensity matching. They responded to a tinnitus rating questionnaire and the Tinnitus Handicap Inventory before and after treatment. RESULTS: There was no significant change in the pretreatment and post-treatment audiometric thresholds in either group. There were no significant differences between the pretreatment and post-treatment Tinnitus Handicap Inventory scores or the tinnitus rating scores in either subject group (Student t test). No diagnosis-specific differences were identified. CONCLUSION: High-frequency pulsed electromagnetic energy (Diapulse) at the settings used in the study showed no role in the therapy of patients with chronic tinnitus.

Primary study

Unclassified

Electromagnetic stimulation as a treatment of tinnitus: a pilot study.

期刊 Clinical otolaryngology and allied sciences
Year 1993
連結 Pubmed DOI

此文章收錄於 1 Systematic review Systematic reviews (1 reference)

Loading references information
This paper reports the results of a study to determine whether pulsed electromagnetic stimulation, applied over the mastoid bone, caused an improvement in the level of tinnitus in long-standing tinnitus sufferers. Fifty-eight patients from the Liverpool Tinnitus Association volunteered to take part in a double-blind placebo controlled trial. Active and placebo devices were randomly allocated to these patients on their first visit. At the end of one week of treatment, each patient noted whether their tinnitus had completely disappeared, was improved, unchanged or made worse by the treatment Forty-five per cent of the patients who completed the trial were improved by the active device, but only 9% by placebo (P = 0.0013, Mann-Whitney test). We suggest that electromagnetic stimulation may be an effective treatment in some tinnitus sufferers.

Primary study

Unclassified

Electromagnetic stimulation as a treatment of tinnitus: a pilot study

期刊 Clinical Otolaryngology & Allied Sciences
Year 1993
連結 DOI Google Scholar

此文章收錄於 1 Systematic review Systematic reviews (1 reference)

Loading references information
This paper reports the results of a study to determine whether pulsed electromagnetic stimulation, applied over the mastoid bone, caused an improvement in the level of tinnitus in long-standing tinnitus sufferers. Fifty-eight patients from the Liverpool Tinnitus Association volunteered to take part in a double-blind placebo controlled trial. Active and placebo devices were randomly allocated to these patients on their first visit. At the end of one week of treatment, each patient noted whether their tinnitus had completely disappeared, was improved, unchanged or made worse by the treatment. Forty-five per cent of the patients who completed the trial were improved by the active device, but only 9% by placebo (P= 0.0013, Mann-Whitney test). We suggest that electromagnetic stimulation may be an effective treatment in some tinnitus sufferers.