Primary studies included in this systematic review

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Primary study

Unclassified

脊髓损伤神经源性膀胱的防腐（SINBA）试验。

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期刊 Spinal cord
Year 2007
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目的：确定是否胺马尿酸（MH）或蔓越莓片预防尿路感染（UTI），脊髓损伤（SCI）后神经性膀胱的人。 研究设计：双盲析因设计随机对照试验（RCT），2年招聘期限从2000年11月和6个月的随访。 设定：共有543资格，主要是社区居住的患者被邀请参加了这项研究，其中305例（56％）同意。 方法：符合条件的参加者的脊髓损伤神经源性膀胱和稳定的膀胱管理的人。所有方案在外观和味道上没有明显区别。MH使用的剂量为1 g，每日两次。蔓越莓使用的剂量为800毫克，每天两次。主要结果是有症状的尿路感染发生的时间。 结果：多因素分析显示，患者随机分配到MH没有一个显著UTI无期比安慰剂组（HR 0.96，95％CI：0.68-1.35，P = 0.75）。患者随机分为酸果蔓同样没有显着UTI-周期相比，安慰剂组（HR 0.93，95％CI：0.67-1.31，P = 0.70）。 结论：在预防泌尿道感染是没有任何好处的MH或蔓越莓片通常的治疗方案的患者脊髓损伤后神经性膀胱。

Primary study

Unclassified

尿预防与六亚甲基四胺在妇科手术中的价值。

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作者 Schiøtz HA , Guttu K
期刊 Acta obstetricia et gynecologica Scandinavica
Year 2002
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背景：有妇科手术后术后菌尿和尿路感染的高风险。术后无症状性菌尿往往消失，不用治疗，但15-20％的患者需要术后尿路感染的治疗。本研究胺马尿酸常规妇科手术后预防​​性治疗的价值进行了评估。 方法：这是一项前瞻性，随机，双盲，安慰剂对照的临床试验，包括145例患者进行常规的妇科剖腹手术或阴道整形外科使用导尿管24小时。不使用抗生素。主题1克Hiprex或安慰剂，每天两次，连续5天。尿培养术前，拔除尿管，2天后。培养阳性的患者给予抗生素治疗，除非他们有症状。随访期为1个月。 统计数据：用卡方检验，Fisher精确检验，t检验显着性水平为0.05，比值比95％的置信区间分别计算。 结果：被诊断为无症状性菌尿，安慰剂组36例（50.0％），22例（30.1％），六亚甲基四胺组（P = 0.02）。被诊断为尿路感染，而安慰剂组10例（13.9％）和2例（2.7％），六亚甲基四胺组（P = 0.03）。有一些不良反应事件。 结论：马尿酸乌洛托品预防性治疗显着减少术后菌尿和尿路感染的发病率。

Primary study

Unclassified

Are prophylactic antibiotics necessary during extracorporeal shockwave lithotripsy?

期刊 British journal of urology
Year 1989
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A randomised clinical study was carried out on patients admitted for ESWL treatment in order to establish the requirement for prophylactic treatment with antibiotics during this procedure. Patients with clinical signs of urinary tract infection, evidence of infectious stones or a positive urine culture were excluded. All other patients were consecutively randomised into 3 groups which were given either trimethoprim + sulphamethoxazole or mecillinam (Group A), methenamine hippurate (Group B), or no treatment at all (Group C). Evaluation with respect to clinical signs of infection was done immediately after the treatment and 4 weeks later. In addition, a urine culture was performed 2 weeks after ESWL, i.e. 1 week after completing treatment with antibiotics and methenamine hippurate. With respect to infectious complications there were no differences between Groups A and C, between Groups B and C or between Group A and B+C, whereas an unexplained slightly higher infectious rate was recorded for Group B compared with Group A. In all patients the occurrence of bacteriuria was low (6.7%) despite the fact that almost 30% of patients had a ureteric catheter during the ESWL procedure. Patients with ureteric catheters did not present with more infectious complications than those without. All patients had a bladder catheter during ESWL. It was concluded that prophylactic treatment with antibiotics during ESWL treatment is unnecessary in all situations where an infectious aetiology is unlikely.

Primary study

Unclassified

Are Prophylactic Antibiotics Necessary during Extracorporeal Shockwave Lithotripsy?

期刊 British Journal of Urology
Year 1989
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A randomised clinical study was carried out on patients admitted for ESWL treatment in order to establish the requirement for prophylactic treatment with antibiotics during this procedure. Patients with clinical signs of urinary tract infection, evidence of infectious stones or a positive urine culture were excluded. All other patients were consecutively randomised into 3 groups which were given either trimethoprim + sulphamethoxazole or mecillinam (Group A), methenamine hippurate (Group B), or no treatment at all (Group C). Evaluation with respect to clinical signs of infection was done immediately after the treatment and 4 weeks later. In addition, a urine culture was performed 2 weeks after ESWL, i.e. 1 week after completing treatment with antibiotics and methenamine hippurate. With respect to infectious complications there were no differences between Groups A and C, between Groups B and C or between Group A and B + C, whereas an unexplained slightly higher infectious rate was recorded for Group B compared with Group A. In all patients the occurrence of bacteriuria was low (6.7%) despite the fact that almost 30% of patients had a ureteric catheter during the ESWL procedure. Patients with ureteric catheters did not present with more infectious complications than those without. All patients had a bladder catheter during ESWL. It was concluded that prophylactic treatment with antibiotics during ESWL treatment is unnecessary in all situations where an infectious aetiology is unlikely.

Primary study

Unclassified

Urinary tract infection after vaginal surgery. Effect of prophylactic treatment with methenamine hippurate.

期刊 Acta obstetricia et gynecologica Scandinavica
Year 1986
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One hundred and nine consecutive patients undergoing surgery for uterovaginal prolapse followed by indwelling urinary catheter for 3 days were randomized for prophylactic treatment with methenamine hippurate (MH) or no MH prophylaxis. Significantly less bacteriuria occurred in the MH-treated patient group. In particular, the opportunistic hospital flora appeared to be suppressed by MH treatment. It is suggested that MH prophylaxis, 1 g three times daily, be used in gynecological surgery followed by short-term urinary catheterization.

Primary study

Unclassified

[中老年妇女经常性膀胱炎。一项双盲比较Hiprex和安慰剂的普遍做法。

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期刊 Tidsskrift for den Norske lægeforening : tidsskrift for praktisk medicin, ny række
Year 1986
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Primary study

Unclassified

在脊髓损伤患者预防尿路感染的预防性抗菌治疗。

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期刊 The Journal of urology
Year 1985
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男科医院161例患者进行了202次试验，以确定是否预防性管理的抗坏血酸或抗菌药物（复方新诺明，萘啶酸，马尿酸乌洛托品或呋喃妥macrocrystals的）会妨碍性菌感染的脊髓损伤患者至少有1回合的菌尿。试验药物没有出现在统计上有效地防止菌尿在这些患者中使用的剂量。此外，敏感性分别输给了其他几种药物用于预防。我们的结论是预防剂量的抗坏血酸或抗菌药物的使用已被证明是有益的脊髓损伤患者留置导管。

Primary study

Unclassified

[六亚甲基四胺马尿酸。在妇科手术中的短期导尿。Hiprex和安慰剂的双盲比较]。

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作者 Knoff T
期刊 Tidsskrift for den Norske lægeforening : tidsskrift for praktisk medicin, ny række
Year 1985
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Primary study

Unclassified

[Prevention of recurrent cystitis in fertile women. A double-blind comparison of Hiprex and placebo in general practice].

期刊 Tidsskrift for den Norske laegeforening : tidsskrift for praktisk medicin, ny raekke
Year 1984
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Primary study

Unclassified

[六亚甲基四胺马尿酸（Haiprex）的短期导尿后尿路感染的预防作用。的临床研究。

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期刊 Ugeskrift for laeger
Year 1984
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