Wen 2012
ID: 648002d4dc6f29f8f96da1cd
2 Documents
Close
2 References ( articles) loading Revert Studify

Primary study

Unclassified

Effectiveness of home based early intervention on children's BMI at age 2: randomised controlled trial.

Journal BMJ (Clinical research ed.)
Year 2012
Links Pubmed DOI PubMed Central

This article is included in 6 Systematic reviews Systematic reviews (6 references)

Loading references information
OBJECTIVE: To assess the effectiveness of a home based early intervention on children's body mass index (BMI) at age 2. DESIGN: Randomised controlled trial. SETTING: The Healthy Beginnings Trial was conducted in socially and economically disadvantaged areas of Sydney, Australia, during 2007-10. PARTICIPANTS: 667 first time mothers and their infants. INTERVENTION: Eight home visits from specially trained community nurses delivering a staged home based intervention, one in the antenatal period, and seven at 1, 3, 5, 9, 12, 18 and 24 months after birth. Timing of the visits was designed to coincide with early childhood developmental milestones. MAIN OUTCOME MEASURES: The primary outcome was children's BMI (the healthy BMI ranges for children aged 2 are 14.12-18.41 for boys and 13.90-18.02 for girls). Secondary outcomes included infant feeding practices and TV viewing time when children were aged 2, according to a modified research protocol. The data collectors and data entry staff were blinded to treatment allocation, but the participating mothers were not blinded. RESULTS: 497 mothers and their children (75%) completed the trial. An intention to treat analysis in all 667 participants recruited, and multiple imputation of BMI for the 170 lost to follow-up and the 14 missing, showed that mean BMI was significantly lower in the intervention group (16.53) than in the control group (16.82), with a difference of 0.29 (95% confidence interval -0.55 to -0.02; P=0.04). CONCLUSIONS: The home based early intervention delivered by trained community nurses was effective in reducing mean BMI for children at age 2. TRIAL REGISTRATION: Australian Clinical Trial Registry No 12607000168459.

Primary study

Unclassified

Economic evaluation of "healthy beginnings" an early childhood intervention to prevent obesity.

blocked
Authors Hayes A , Lung T , Wen LM , Baur L , Rissel C , Howard K
Journal Obesity (Silver Spring, Md.)
Year 2014
Links Pubmed Health Technology Assessment (HTA) DOI crd.york.ac.uk

This article is included in 1 Systematic review Systematic reviews (1 reference)

Loading references information
OBJECTIVE: To determine the costs and cost-effectiveness of an early childhood home visiting program delivered to families in socio-economically disadvantaged areas of Sydney, Australia during 2007-2010. METHODS: Economic evaluation of a randomized controlled trial, the healthy beginnings (HB) trial, from the perspective of the health funder. Intervention resources were determined from local health district records in 2012 $AUD. Health-care resource utilization was determined through patient-level data linkage. RESULTS: The cost of HB intervention in the clinical trial over 2 years was $1309 per child (2012 $AUD). The incremental cost-effectiveness ratio was $4230 per unit BMI avoided and $631 per 0.1 reduction in BMI z-score. It was estimated that the program could be delivered in practice for $709 per child; with incremental cost-effectiveness ratios of $2697 per unit BMI avoided and $376 per 0.1 reduction in BMI z-score. CONCLUSIONS: We present the first economic evaluation of an effective obesity prevention initiative in early childhood. HB is a moderately priced intervention with demonstrated effectiveness that offers similar or better value for money than existing obesity prevention or treatment interventions targeted at older children.