La dosis óptima y la vía de administración de metotrexato en la artritis reumatoide: una revisión sistemática de la literatura

Autores
Categoría Resumen estructurado de revisiones sistemáticas
RevistaDatabase of Abstracts of Reviews of Effects (DARE)
Año 2010
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CRD SUMMARY:

The optimal dosage and route of administration of methotrexate in patients with rheumatoid arthritis was to start at 15mg per week orally, escalate by 5mg per month up to 25 to 30mg per week, or the highest tolerable dose, and then change to subcutaneous administration for insufficient responders. The review’s limitations make the reliability of the authors’ conclusions unclear.
Epistemonikos ID: 1873e07767a21fb68bbae47d45f58626aeb4ae99
First added on: Jun 07, 2012