Azithromycin compared with clarithromycin for the treatment of streptococcal pharyngitis in children.

Aún no traducido Aún no traducido
Categoría Estudio primario
RevistaThe Journal of international medical research
Año 1998

Este artículo está incluido en 1 Revisión sistemática Revisiones sistemáticas (1 referencia)

Este artículo es parte de las siguientes matrices de evidencia
Cargando información sobre las referencias
The treatment of streptococcal pharyngitis with azithromycin (10 mg/kg orally once daily for 3 days) or clarithromycin (7.5 mg/kg orally twice daily for 10 days) was compared in a randomized observer-blind study carried out in 174 children with documented Streptococcus pyogenes infection. The observed cure rate 10 days after the beginning of treatment was 61/63 (96.8%) in the clarithromycin group and 71/74 (95.9%) in the azithromycin group. At days 17-20 the bacteriological eradication rate was 95.2% for clarithromycin and 94.6% for azithromycin. When children who did not complete treatment were included in the analysis the eradication rate was higher for azithromycin (93.6% compared with 82.9%; P < 0.05); the difference was due to better compliance with the azithromycin regimen.
Epistemonikos ID: 1c114d995a61aae345287be36f99e72f1506000a
First added on: Nov 22, 2016