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Estudio primario

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Revista Journal of cardiac failure
Año 2020
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<b>BACKGROUND: </b>Practical recommendations on nonpharmacologic non-device/surgical interventions in patients with heart failure (HF) are well known. Although complementary treatments may have beneficial effects, there is no evidence that these on their own improve mortality, morbidity, or quality of life. We examined the effects of listening to recorded classical music on HF-specific quality of life (QOL), generic QOL, sleep quality, anxiety, depression, and cognitive state in patients with HF in the home-care setting.<b>METHODS AND RESULTS: </b>Multicenter randomized controlled trial. One hundred fifty-nine patients with HF were randomized on a 1:1 basis in 2 groups: experimental (music) and control. Patients were evaluated after 30, 60, 90 days (experimental period) and at 6 months. Patients randomized to the music group listened to music from a large preselected playlist, at least 30 minutes per day, for 3 months on an MP3 player. Patients in the control group received standard care. HF-specific QOL, generic QOL, self-care, somatic perception of HF symptoms, sleep quality, anxiety and depression, and cognitive abilities were assessed throughout the use of specific scales. On average, patients in the music group showed greater improvements in terms of HF-specific QOL (P &lt; .001), generic-QOL (P = .005), quality of sleep (P = .007), anxiety and depression levels (P &lt; .001 for both), and cognitive performances (P = .003).<b>CONCLUSIONS: </b>Listening to recorded classical music is a feasible, noninvasive, safe, and inexpensive intervention, able to improve QOL in patients with HF in the home-care setting.

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Revista Journal of Kermanshah University of Medical Sciences
Año 2019
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Objectives: Although some studies have shown the effectiveness of music therapy on insomnia (secondary insomnia), no study has so far investigated the effectiveness of music therapy with Persian traditional music on the treatment of primary insomnia. Therefore, the purpose of this study was to evaluate the effectiveness of music therapy with Persian traditional music on the treatment of primary insomnia. Methods: This study was a controlled clinical trial with 30 participants with primary insomnia. Participants were randomly assigned to intervention (N = 15) and control (N = 15) groups. Pittsburgh sleep quality index (PSQI), insomnia severity index (ISI), and depression, anxiety and stress scales (DASS-21) were used to evaluate the intervention results. Anxiety, stress, depression, insomnia and sleep quality were measured before and six weeks after the intervention. Results: One-wayANCOVAresults showed that music therapy with Persian traditional music significantly improved insomnia, sleep quality and depression in the intervention group. There was however no significant difference between the two groups in terms of anxiety and stress. Conclusions: Persian traditional music can be used as an effective and cost-effective way to improve sleep quality and reduce depression associated with primary insomnia.

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Revista Journal of sleep research
Año 2019
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Summary Music is often used as a self‐help tool to alleviate insomnia. To evaluate the effect of bedtime music listening as a strategy for improving insomnia, we conducted an assessor‐blinded randomized controlled trial. Fifty‐seven persons with insomnia disorder were included and randomized to music intervention (n = 19), audiobook control (<i>n</i> = 19) or a waitlist control group (<i>n</i> = 19). The primary outcome measure was the Insomnia Severity Index. In addition, we used polysomnography and actigraphy to evaluate objective measures of sleep, and assessed sleep quality and quality of life. The results showed no clear effect of music on insomnia symptoms as the group × time interaction only approached significance (effect size = 0.71, <i>p</i> = .06), though there was a significant improvement in insomnia severity within the music group. With regard to the secondary outcomes, we found a significant effect of the music intervention on perceived sleep improvement and quality of life, but no changes in the objective measures of sleep. In conclusion, music listening at bedtime appears to have a positive impact on sleep perception and quality of life, but no clear effect on insomnia severity. Music is safe and easy to administer, but further research is needed to assess the effect of music on different insomnia subtypes, and as an adjunctive or preventive intervention. (PsycInfo Database Record (c) 2022 APA, all rights reserved)

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Revista European Journal of Integrative Medicine
Año 2018
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Estudio primario

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Autores Huang CY , Chang ET , Hsieh YM , Lai HL
Revista Complementary therapies in medicine
Año 2017
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<b>OBJECTIVES: </b>The present study aimed to compare the effects of music and music video interventions on objective and subjective sleep quality in adults with sleep disturbances.<b>DESIGN: </b>A randomized controlled trial was performed on 71 adults who were recruited from the outpatient department of a hospital with 1100 beds and randomly assigned to the control, music, and music video groups.<b>INTERVENTIONS: </b>During the 4 test days (Days 2-5), for 30min before nocturnal sleep, the music group listened to Buddhist music and the music video group watched Buddhist music videos. They were instructed to not listen/watch to the music/MV on the first night (pretest, Day 1) and the final night (Day 6). The control group received no intervention.<b>MAIN OUTCOME MEASURES: </b>Sleep was assessed using a one-channel electroencephalography machine in their homes and self-reported questionnaires.<b>RESULTS: </b>The music and music video interventions had no effect on any objective sleep parameters, as measured using electroencephalography. However, the music group had significantly longer subjective total sleep time than the music video group did (Wald χ2=6.23, p=0.04).<b>CONCLUSION: </b>Our study results increase knowledge regarding music interventions for sleep quality in adults with sleep disturbances. This study suggested that more research is required to strengthen the scientific knowledge of the effects of music intervention on sleep quality in adults with sleep disturbances. (ISRCTN94971645).

Estudio primario

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Autores Liu YH , Lee CS , Yu CH , Chen CH
Revista Women & health
Año 2016
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Prenatal sleep disturbance has been associated with undesirable birthing outcomes. To determine the effectiveness of listening to music at home in improving sleep quality, 121 Taiwanese pregnant women with poor sleep quality (Pittsburgh Sleep Quality Index [PSQI] score &gt; 5) were systematically assigned, with a random start to music listening (n = 61) or control (n = 60) group. Participants in the music listening group self-regulated listening to music in addition to receiving general prenatal care similar to that in the control group for 2 weeks. The PSQI and State-Anxiety Inventory were used to assess outcomes. ANCOVA analyses were used with the pretest scores as covariates and showed significant improvement in sleep quality, stress, and anxiety in the music listening group compared with the control group. The most frequently used music genre by participants in the experimental group was lullabies, followed by classical music and crystal baby music. This study supported the theory that 2-week music listening interventions may reduce stress, anxiety, and yield better sleep quality for sleep-disturbed pregnant women. The analysis of participants’ journals also implied that the expectant mothers’ choices of musical genres may correlate more with perceived prenatal benefits or the desire to interact with their unborn child.

Estudio primario

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Autores Wang Q , Chair SY , Wong EM , Li X
Revista Journal of alternative and complementary medicine (New York, N.Y.)
Año 2016
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OBJECTIVES: To examine the effects of music intervention on sleep quality in community-dwelling elderly people. DESIGN: Two-armed randomized controlled trial. Settings: Four urban communities in Xi'an, China. Participants: People aged 60 years or older with poor sleep quality (Pittsburgh Sleep Quality Index [PSQI] score &gt; 7). INTERVENTIONS: All participants received one sleep hygiene education session and biweekly telephone calls. Each participant in the intervention group received an MP3 player with a music database. The participants selected the preferred music and listened for 30–45 minutes per night for 3 months. Outcome measures: Sleep quality, the main study outcome, was measured by PSQI at baseline, 1 month, 2 months, and 3 months. RESULTS: Sixty-four elderly people with a mean age of 69.38 ± 5.46 years were randomly assigned to the control group (<i>n</i> = 32) or the intervention group (<i>n</i> = 32). All participants completed the study, and none reported discomfort related to the music intervention. The intervention group demonstrated continuous improvements in sleep quality, with a global PSQI score of 13.53 at baseline, 9.28 at 1 month, 8.28 at 2 months, and 7.28 at 3 months. Although the global PSQI score in the control group also decreased from 12.26 at baseline to 8.72 at 3 months, the intervention group achieved greater improvements at each measurement (all <i>p</i> &lt; 0.05). Repeated-measures analysis of variance revealed significant group-by-time interaction effects in global PSQI score and three component scores: sleep latency, sleep efficiency, and daytime dysfunction (all <i>p</i> &lt; 0.05). CONCLUSION: Music is a safe and effective nonpharmacological intervention for improving the sleep quality of community-dwelling elderly people, especially in improving sleep latency, sleep efficiency, and daytime dysfunction. (PsycInfo Database Record (c) 2022 APA, all rights reserved)

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Registro de estudios clinicaltrials.gov
Año 2015
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The aim of this study is to determine the effect of listening to music on sleep quality (subjective and objective), daytime dysfunction and neurophysiological arousal in patients with insomnia.

Estudio primario

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Autores Cai X-M , Zhang X-P , Tang X.
Revista Journal of Acupuncture and Tuina Science
Año 2015
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Revista Clinical interventions in aging
Año 2014
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PURPOSE: A link between poor sleep quality and Alzheimer's disease (AD) has recently been suggested. Since endogenous melatonin levels are already reduced at preclinical AD stages, it is important to ask whether replenishing the missing hormone would be beneficial in AD and whether any such effects would be related to the presence of sleep disorder in patients. PATIENTS AND METHODS: The effects of add-on prolonged-release melatonin (PRM) (2 mg) to standard therapy on cognitive functioning and sleep were investigated in 80 patients (men [50.7%], women [49.3%], average age 75.3 years [range, 52-85 years]) diagnosed with mild to moderate AD, with and without insomnia comorbidity, and receiving standard therapy (acetylcholinesterase inhibitors with or without memantine). In this randomized, double-blind, parallel-group study, patients were treated for 2 weeks with placebo and then randomized (1:1) to receive 2 mg of PRM or placebo nightly for 24 weeks, followed by 2 weeks placebo. The AD Assessment Scale-Cognition (ADAS-Cog), Instrumental Activities of Daily Living (IADL), Mini-Mental State Examination (MMSE), sleep, as assessed by the Pittsburgh Sleep Quality Index (PSQI) and a daily sleep diary, and safety parameters were measured. RESULTS: Patients treated with PRM (24 weeks) had significantly better cognitive performance than those treated with placebo, as measured by the IADL (P=0.004) and MMSE (P=0.044). Mean ADAS-Cog did not differ between the groups. Sleep efficiency, as measured by the PSQI, component 4, was also better with PRM (P=0.017). In the comorbid insomnia (PSQI ≥6) subgroup, PRM treatment resulted in significant and clinically meaningful effects versus the placebo, in mean IADL (P=0.032), MMSE score (+1.5 versus -3 points) (P=0.0177), and sleep efficiency (P=0.04). Median ADAS-Cog values (-3.5 versus +3 points) (P=0.045) were significantly better with PRM. Differences were more significant at longer treatment duration. PRM was well tolerated, with an adverse event profile similar to that of placebo. CONCLUSION: Add-on PRM has positive effects on cognitive functioning and sleep maintenance in AD patients compared with placebo, particularly in those with insomnia comorbidity. The results suggest a possible causal link between poor sleep and cognitive decline.