Three-year follow-up of protease inhibitor-based regimen simplification in HIV-infected patients.

Categoría Estudio primario
RevistaAIDS (London, England)
Año 2007
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Patients with sustained virological suppression on protease inhibitor (PI)-based therapy were randomly assigned to switch the PI to nevirapine (n = 155), efavirenz (n = 156), or abacavir (n = 149) and were followed for at least 3 years regardless of the discontinuation of assigned therapy. There was a higher probability of maintaining virological suppression after 3 years of follow-up with nevirapine or efavirenz than with abacavir. In contrast, abacavir showed a lower incidence of adverse effects leading to drug discontinuation.
Epistemonikos ID: 8336afd320ffc3665074d9a8661068a2e960c897
First added on: Jun 22, 2013