Una revisión sistemática de ensayos controlados aleatorios de tratamiento farmacológico en la artrosis de la rodilla, con un énfasis en la metodología del ensayo

CRD COMMENTARY:

The search was limited and trials were almost certainly missed, in particular trials published in languages other than English. Although the methodological quality of trials was assessed, the method has not been validated and these results were not mentioned in the discussion of trial outcomes.
This review contains information about many different drug comparisons, but the way it is presented limits its usefulness. The authors' overall efficacy measure does not appear to allow for sample size, nor are there any figures for statistical significance of differences between treatment effects. More detail, in particular confidence intervals, would have been helpful.