CTE, CE, SBFT, MRE for Crohn's disease diagnostic evaluation system

Objective To evaluate the CTE (including CT angiography method and CT intestinal bowel movement plethysmography), capsule endoscopy (CE), MR bowel movement plethysmography (MRE) and small bowel barium meal (SBFT) for Crohn's disease (CD) diagnostic accuracy degrees. PICO retrieval method follows the principle of Medline (1960 ~ 2010), PubMed, CBM, EMBASE, CCTR, Cochrane Library and other databases, combined with manual searches, included in the assessment or comparison CTE, CE, SBFT, MRE for Crohn's disease prospective or retrospective diagnostic tests. According to the quality of the literature included QUADAS quality evaluation criteria. The combined sensitivity of the detection method described above (SEN), merger specificity (SPE), the combined positive likelihood ratio (+ LR), the combined negative likelihood ratio (-LR) and the generality of the receiver operating characteristic curve (SROC) under the area. The results were included in the literature 9, a total of 360 cases. Reference standards include: ① endoscopy, pathology and imaging technology methods; ② ileocolonoscopy + surgery or biopsy results. There were four and five research ① and ② as the reference standard, the SEN were 0.77 (95% CI0.69 ~ 0.84), 0.86 (95% CI 0.80 ~ 0.90), SPE was 0.81 (95% CI 0.72 ~ 0.88), 0.97 (95% CI 0.89 ~ 1.00), + LR was 3.44 (95% CI1.61 ~ 7.32) 1,4.67 (95% CI 5.31 ~ 40.50), - LR was 0.30 (95% CI 0.18 ~ 0.50), 0.16 (95% CI 0.11 ~ 0.22), the area under the SROC curve was 0.8762 and 0.8429 respectively. CTE for Crohn's disease in which the sensitivity and specificity and the largest, followed for SBFT, MRE and CE. Conclusion In the comparison of four kinds of inspection techniques, CTE diagnosis of Crohn's disease most accurate.