Addition of theophylline or increasing the dose of inhaled corticosteroid in symptomatic asthma: a meta-analysis of randomized controlled trials.

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作者
类别 Systematic review
期刊Yonsei medical journal
Year 2011
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目的:低剂量茶碱具有抗炎作用。本研究的目的是评估增加茶碱的影响相比,增加剂量吸入糖皮质激素(ICS)的哮喘症状。
材料与方法:刻意寻找相关文献获得通过,并选择的基础上建立出版物纳入标准。一项荟萃分析,提取的数据进行进一步分析。
结果:四随机,对照,平行研究。此外茶碱产生了一秒钟用力呼气容积较大的提高,随着%的预测(容积₁预计值)由2.49%[95%可信区间(CI)1.99-3.00; Z = 9.70,P <0.001]相比增加剂量, ICS的。呼气峰流速两种治疗(PEF)之间没有差异。
结论:除了以ICS的茶碱有类似的治疗效果增加剂量的ICS治疗哮喘症状,改善肺功能。
Epistemonikos ID: 15a553b113695e51217c0ff055506347a2760ecf
First added on: Dec 19, 2011
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