Early hospital discharge followed by outpatient management versus continued hospitalization of children with cancer, fever, and neutropenia at low risk for invasive bacterial infection.

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类别 Primary study
期刊Journal of clinical oncology : official journal of the American Society of Clinical Oncology
Year 2004
連結 Pubmed, Health Technology Assessment (HTA), DOI , crd.york.ac.uk

此文章收錄於 5 Systematic reviews Systematic reviews (5 references)

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目的：比较结果和门诊发热与中性粒细胞减少儿童的住院费用管理风险较低侵袭性细菌感染（IBI）。
病人与方法：儿童发热性中性粒细胞减少在智利圣地亚哥六医院介绍，被归类为高风险或低风险的IBI。低风险的儿童被随机分配24至36小时住院后接收卧床或住院治疗和监测，直到插曲分辨率。结果和成本确定为每一集和两组使用预定义的定义和问卷进行比较。
结果：共有161（41％）的评估2000年6月至2003年2 390中性粒细胞减少性发热事件被归类为低风险，其中149被随机分配到门诊（N = 78）或医院为基础的（N = 71）治疗。在这两个群体，平均年龄（动态管理，有55个月;以医院为基础的管理，66个月），性别和癌症类型相似。结果是在74（95％）的有利门诊78处理71医院治疗的儿童（P = NS）的儿童和67（94％）。一个小插曲的平均成本为638美元（95％CI，572美元到703美元）和美国903美元（95％CI，781美元〜1025美元）的门诊和医院为基础的团体，分别为（P = 0.003 ）。
结论：对于小儿发热性中性粒细胞减少在低风险的IBI，动态管理是安全的，显著节省成本与标准的住院治疗相比。
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Epistemonikos ID: 70d9aaca3ed4ed8b15e29e9cfb3be6290442518b
First added on: Feb 23, 2015
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