Chemoprophylaxis of bacterial infections in granulocytopenic cancer patients using norfloxacin.

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类别 Primary study
期刊Chemioterapia : international journal of the Mediterranean Society of Chemotherapy
Year 1988
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六十五名癌症病人化疗或放疗预处理粒细胞低于1000/mm3的,没有发烧,进入本研究:其中30人已提交预防与诺氟沙星,而其余的35例作为对照组。 68.6%的控制与治疗的受试者的20%提出后续的感染(p小于0.001),肺癌占传染病的最频繁的网站(分别为3/6和14/24)两组。这些数据有力地表明,诺氟沙星在nonfebrile,granulocytopenic癌症患者作为一种有效的预防性药物的使用,特别尽可能革兰氏阴性菌感染有关。因为在我们研究的患者中,肺癌和肺部感染相关的患病率在目前的时间,高患病率,每一种固体肿瘤的这种抗生素的广泛使用,不能一概而论。
Epistemonikos ID: 8a5bdd75b863dfd3aa0b8a3e8a487fb6fae2ef4e
First added on: Jan 31, 2012
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