Effects of oral and intramuscular vitamin K prophylaxis on vitamin K1, PIVKA-II, and clotting factors in breast fed infants.

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类别 Primary study
期刊Archives of disease in childhood
Year 1992
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一项随机临床试验进行了建立口服和肌肉注射维生素K的影响在出生时血药浓度的维生素K1,维生素K缺乏(PIVKA-II),和凝血因子诱导的蛋白质。两组约165名健康母乳喂养的婴儿谁收到随机1毫克维生素K1口服或肌注出生后的2周和1个月和3个月的年龄进行了研究。维生素K1的浓度虽然有统计学显着高于肌肉注射组​​,血液凝固因子VII和X和PIVKA-II的活动的浓度没有透露任何两组之间的差异。在2周龄提出了报告的未浓度没有PIVKA-II检测相比,维生素K1的浓度。维生素K1浓度分别为3个月的未价值观和PIVKA-II检测在11.5%的婴儿。因此,反复口腔预防将要完全防止维生素K缺乏症(生化)超过1个月的年龄。
Epistemonikos ID: a76ba1c1fd645f05eff2508b6096c234a54246b0
First added on: Feb 05, 2013
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