Vitamin A supplementation enhances specific IgG antibody levels and total lymphocyte numbers while improving morbidity in measles.

Machine translation Machine translation
类别 Primary study
期刊The Pediatric infectious disease journal
Year 1992
連結 Pubmed, DOI
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非洲儿童（年龄4个月至24个月与复杂的麻疹）进行了测试，随机双盲干预试验过程中补充维生素A在选定的免疫因素的影响。安慰剂组（n = 31）和治疗组（n = 29）的基线特征相似。的补充组有显着降低发病率（集成的发病率分数）在急性期（第8天，P = 0.006）和慢性（42天，P = 0.02; 6个月，P = 0.002）阶段。在治疗组有增加淋巴细胞总数（第42天，P = 0.05）和麻疹IgG抗体浓度（第8天，P = 0.02），这两个一直被先前的研究显示，与结果的关系更密切的合作比其他免疫，麻疹临床和影像学因素。补充维生素A，白细胞介素2和血浆补值并没有受到影响。这些调查结果加强动物实验研究结果表明，维生素A的活性，降低发病率和死亡率的途径是部分建立在选择性的免疫增强作用。
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Epistemonikos ID: aded3b80a498fed15d0094c6341b6aee22569e09
First added on: Nov 25, 2012
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