Similar efficacy of ciclesonide once daily versus fluticasone propionate twice daily in patients with persistent asthma.

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类别 Primary study
期刊The Journal of asthma : official journal of the Association for the Care of Asthma
Year 2007
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这12周,双盲,平行组研究,比较每日一次的环索奈德,年龄12-75年持续性哮喘患者每日两次卡松的疗效和安全性。患者被随机分配到每日一次的环索奈德80微克(N = 278)或160微克(N = 271),或每天两次替卡松88微克(N = 259)(所有前执行器)。从基线显着改善被视为在所有三个治疗用力呼气量在1秒,哮喘症状评分和抢救用药组(P <0.0001)。哮喘发作率分别为低(每个环索奈德组,N = 2;氟替卡松组,n = 1)。不良事件报告显示良好的耐受性。一旦每天的环索奈德80微克或160微克显示可比的疗效和耐受性,每日两次替卡松88微克,持续性哮喘。
Epistemonikos ID: c3dfab70379e017bbf088083549f3ce1e5cce196
First added on: Jun 08, 2011
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