Riluzole therapy in cervical dystonia.

Categoría Estudio primario
RevistaMovement disorders : official journal of the Movement Disorder Society
Año 2002
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We conducted a 6-week open-label pilot study with blinded video rating of riluzole (50 mg twice a day) in six patients with cervical dystonia (CD) refractory to botulinum toxin A and oral pharmacological treatment. The Tsui rating scale served as primary efficacy measure and improved significantly under riluzole (P = 0.002). In three of six patients, the Tsui score improved by more than 30% with a greater 50% reduction in the head tremor/jerk subscore of the Tsui scale. These data suggest that riluzole may be helpful in a subgroup of patients with disabling CD refractory to other therapies.
Epistemonikos ID: 8f7e9009dfc117026395b9c907fcfbf22e722a3b
First added on: Nov 07, 2017