El impacto de los trastornos de la personalidad en los resultados del consumo de alcohol en un ensayo de tratamiento farmacológico para la dependencia del alcohol y los trastornos comórbidos del Eje I.

Categoría Estudio primario
RevistaThe American journal on addictions / American Academy of Psychiatrists in Alcoholism and Addictions
Año 2007

Este artículo está incluido en 3 Revisiones sistemáticas Revisiones sistemáticas (3 referencias)

Este artículo es parte de los siguientes hilos de publicación
Este artículo es parte de las siguientes matrices de evidencia
Cargando información sobre las referencias
Although antisocial and borderline personality disorders frequently co-occur with alcohol dependence and other Axis I disorders, their effect on alcohol use outcomes in context of pharmacotherapy remains unclear. Patients with Major Axis I disorders, including alcohol dependence, and diagnosis of antisocial (ASPD) or borderline personality disorder (BPD) were enrolled in a 12-week medication trial for treatment of their alcohol dependence. Everyone was randomized to one of four cells: naltrexone alone, placebo alone, open label disulfiram and naltrexone, or open label disulfiram and placebo. Outcome measures included scales for alcohol use and craving. Data were analyzed comparing patients with ASPD vs. those without, and patients with BPD vs. those without. Diagnosis of personality disorder did not adversely affect alcohol outcomes, and patients with ASPD or BPD did not have a poorer response to medication than patients without diagnosis of ASPD or BPD. The findings suggest that naltrexone and disulfiram can be safely and effectively used with patients who have comorbid diagnoses of Axis I and Axis II disorders. (PsycInfo Database Record (c) 2021 APA, all rights reserved)
Epistemonikos ID: e0a1129b461db01b23da6bdb77878cddf2a7ef51
First added on: Jun 08, 2011