Abdominal decompression for suspected fetal compromise/pre‐eclampsia

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作者
类别 Systematic review
期刊Cochrane database of systematic reviews (Online)
Year 2000
虽然大多数研究报道,高血清乳酸脱氢酶(LDH)水平与几种恶性肿瘤的预后差相关,LDH的影响的一致性和幅度尚不清楚。我们进行了LDH在实体瘤中预后相关性的第一次综合荟萃分析。总体生存(OS)是主要结果;无进展生存期(PFS)和无病生存(DFS)是次要结局。我们共确定了68项符合条件的研究,其中包括31,857例患者。高LDH与1.48(95%CI = 1.43至1.53; P <0.00001; I(2)= 93%)的OS的HR相关,在所有疾病亚组,部位,阶段和LDH截断中观察到影响。 PFS和DFS的HR为1.70(95%CI = 1.44〜2.01; P <0.00001; I(2)= 13%)和1.86(95%CI = 1.15〜3.01; P = 0.01; I(2)= 88% ), 分别。 LDH作为连续变量的分析显示,随着LDH升高,OS较差(HR 2.11; 95%CI = 1.35〜3.28)。敏感性分析显示,LDH截止值和报告的OS的HR之间没有关联。高LDH与许多实体瘤的不良预后相关,临床决策的其他预后和预测价值进一步调查。
Epistemonikos ID: e9c03411d560ce73a3d011ae78c4d865702f4260
First added on: Oct 11, 2011
[Current] 怀疑胎儿妥协/先兆子痫的腹部减压
10.1002/14651858.CD000004
[Current] 怀疑胎儿妥协/先兆子痫的腹部减压
10.1002/14651858.CD000004
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