Matriz de evidencia
Corticoides intraarticulares para la artrosis de rodilla
This matrix includes 14 Revisiones Sistemáticas Show Hide

Estudio primario

No clasificado

[Diclofenac iontophoresis in the treatment of arthrosis].

Año 1982
Autores Williame E , Anthoine F , Plissart M
Revista Journal belge de médecine physique et de réhabilitation. = Belgisch tijdschrift voor fysische geneeskunde en rehabilitatie
Enlaces Pubmed

Este artículo está incluido en 1 Revisión sistemática Revisiones sistemáticas (1 referencia)

Cargando información sobre las referencias
Mostrar resumen

Este artículo no tiene resumen

Mostrar resumen

Estudio primario

No clasificado

La ultrasonografía y su rol actual en la artrosis

Traducción oficial
Año 2009
Revista Rev. chil. reumatol
Enlaces Virtual Health Library

Este artículo no está incluido en ninguna revisión sistemática

Cargando información sobre las referencias
Mostrar resumen

La artrosis es un proceso crónico caracterizado por alteraciones degenerativas propias del cartílago articular y modificaciones de tipo proliferativo del tejido óseo adyacente. La producción de equipos ultrasonográficos con transductores de alta frecuencia (>15 MHz) y elevada capacidad de resolución ha constituido un paso fundamental para la consolidación progresiva de este método de imágenes en el campo de estudio de la artrosis, permitiendo una detallada visualización de las distintas estructuras anatómicas (cartílago articular, membrana sinovial y tejido óseo) involucradas en las diferentes etapas del proceso artrósico, Este potencial ofrece relevantes aplicaciones prácticas en esta patología, considerando que generalmente las expresiones clínico-radiológicas de la artrosis tienden a manifestarse con notable retraso respecto a las expresiones iniciales de condropatía. La presente revisión tiene como objetivo principal demostrar la utilidad de la US en el estudio de pacientes con artrosis mediante la ilustración de los hallazgos ecográficos más representativos de dicha entidad.

Mostrar resumen

Revisión sistemática

No clasificado

Clinical efficacy of low power laser therapy in osteoarthritis.

Año 1999
Autores Marks R , de Palma F
Revista Physiotherapy research international : the journal for researchers and clinicians in physical therapy
Enlaces Pubmed

Este artículo está incluido en 1 Resumen estructurado de revisiones sistemáticas 6 Resúmenes estructurados de revisiones sistemáticas (1 referencia)

Este artículo incluye 6 Estudios primarios 6 Estudios primarios (6 referencias)

Cargando información sobre las referencias
Mostrar resumen

BACKGROUND AND PURPOSE:

Of the various physical interventions used to relieve the symptoms of osteoarthritis (OA), a common degenerative joint disease causing considerable pain and disability, low power laser therapy has been reported to be extremely successful in Russia and Eastern Europe.

METHOD:

Although the overall number of studies was small, this literature review and analysis highlights the relevant controlled clinical trials and related basic research in English-language publications. This review indicates that, despite their shortcomings, the six studies analysed did report post-treatment improvements in a variety of osteoarthritic problems, including pain, mobility, tenderness and function, with few adverse effects. Possible mechanisms documented for the observed results included peripheral nerve stimulation, resolution of inflammation, enhanced chondrocyte proliferation and increased matrix synthesis.

CONCLUSION:

Not all studies were affirmative and few detailed how reliable their measurements were. Clearly, much more work is needed in this area.

Mostrar resumen

Revisión sistemática

No clasificado

Clinical effectiveness of mud pack therapy in knee osteoarthritis.

Año 2013
Revista Rheumatology (Oxford, England)
Enlaces Pubmed , DOI

Este artículo incluye 20 Estudios primarios 20 Estudios primarios (20 referencias)

Cargando información sobre las referencias
Mostrar resumen

OBJECTIVE:

The main objective of this study was to systematically review all the scientific studies that analyse the effectiveness of mud pack therapy on patients diagnosed with knee OA.

METHODS:

One hundred and fifteen publications were identified through an electronic and manual search and 20 of those studies were chosen based on the inclusion criteria: randomized clinical trials, systematic reviews or meta-analyses whose objective was to analyse the effect of mud pack therapy on perceived pain, function and quality of life, with a sample size of ≥20 subjects, published since 2000 and showing conclusive results.

RESULTS:

In the studies that met the inclusion criteria, 12 analyse functionality, 17 perceived pain, 5 quality of life and all showed a significant improvement in the three analysed variables. The methodological quality of the studies had a moderate risk of bias.

CONCLUSION:

Mud pack therapy is considered an alternative and effective therapy in the clinical management of knee OA. Studies with better methodology are needed to prove its scope.

Mostrar resumen

Revisión sistemática

No clasificado

Systematic review of the prevalence of radiographic primary hip osteoarthritis.

Año 2009
Revista Clinical Orthopaedics & Related Research
Enlaces PMC , Pubmed , DOI

Este artículo incluye 25 Estudios primarios 25 Estudios primarios (25 referencias)

Cargando información sobre las referencias
Mostrar resumen

Hip osteoarthritis is a common cause of musculoskeletal pain in older adults and may result in decreased mobility and quality of life. Although the presentation of hip osteoarthritis varies, surgical management is required when the disease is severe, longstanding, and unresponsive to nonoperative treatments. For stakeholders to plan for the expected increased demand for surgical procedures related to hip osteoarthritis, including arthroplasty, it is important to first understand its prevalence. We conducted a systematic review by searching MEDLINE and EMBASE to identify recent English language articles reporting on the prevalence of radiographic primary hip osteoarthritis in the general adult population; references including studies and primary studies from previous systematic reviews were also searched. This strategy yielded 23 studies reporting 39 estimates of overall prevalence ranging from 0.9% to 27% with a mean of 8.0% and a standard deviation of 7.0%. Heterogeneity was noted in study populations, eligibility criteria, age and gender distribution, type of radiographs, and method of diagnosis. Although the association between radiographic hip osteoarthritis and the need for eventual surgical management is still unclear, this study supports assertions that hip osteoarthritis is a prevalent condition whose treatment will continue to place important demands on health services.

Mostrar resumen

Estudio primario

No clasificado

Tanezumab In Osteoarthritis Of The Hip Or Knee

Año 2009
Autores Pfizer
Registro de estudios clinicaltrials.gov
Enlaces ClinicalTrials.gov

Este artículo está incluido en 1 Revisión sistemática Revisiones sistemáticas (1 referencia)

Cargando información sobre las referencias
Mostrar resumen

The purpose of the study is to test the efficacy and safety of 2 doses of tanezumab compared to oxycodone CR and placebo in patients with osteoarthritis

Mostrar resumen

Estudio primario

No clasificado

Intra-articular hydrocortisone in osteo-arthrosis.

Año 1967
Autores Shah KD , Wright V
Revista Annals of the rheumatic diseases
Enlaces PMC , Pubmed , DOI

Este artículo está incluido en 2 Revisiones sistemáticas Revisiones sistemáticas (2 referencias) 1 Síntesis amplia Síntesis amplias (1 referencia)

Cargando información sobre las referencias
Mostrar resumen

Este artículo no tiene resumen

Mostrar resumen

Revisión sistemática

No clasificado

Management of depression in older people with osteoarthritis: a systematic review.

Año 2010
Autores Yohannes AM , Caton S
Revista Aging & mental health
Enlaces Pubmed , DOI

Este artículo está incluido en 1 Resumen estructurado de revisiones sistemáticas 15 Resúmenes estructurados de revisiones sistemáticas (1 referencia) 4 Síntesis amplias 15 Síntesis amplias (4 referencias)

Este artículo incluye 15 Estudios primarios 15 Estudios primarios (15 referencias)

Cargando información sobre las referencias
Mostrar resumen

Objectives: Osteoarthritis (OA) is the most common form of arthritis, and depressive symptoms are common in older people with arthritic pain. However, relatively little attention has been given to the efficacy of interventions that may be beneficial for older people with OA with concomitant depressive symptoms. Methods: The aim of this review was to evaluate data from clinical trials testing the effectiveness of various interventions for older patients suffering from OA and depression. Systematic searches were conducted on MEDLINE, CINAHL, Scopus, PsychInfo, Web of Knowledge and Pubmed (January 1990-July 2009). Results: Fourteen studies were identified and examined. Interventions highlighted in these studies were: patient education programmes (N = 3); cognitive behavioural therapy (CBT) (N = 2); depression care and pharmacological intervention (N = 2); and exercise therapy (N = 7). 11 out of 14 interventions showed some improvement in patients' depressive symptoms in the short term. Three of the interventions did not affect depressive symptoms on patients with OA. Conclusions: There was some evidence to suggest that the intervention of CBT, integrated depression care management and exercise therapy were associated with reduced depressive symptoms in the short term. However, the long-term benefits of depression management in patients with OA with co-morbid depression are unknown. Future well-controlled clinical trials are needed.

Mostrar resumen

Revisión sistemática

No clasificado

Synovial inflammation, immune cells and their cytokines in osteoarthritis: a review.

Año 2012
Revista Osteoarthritis and cartilage / OARS, Osteoarthritis Research Society
Enlaces Pubmed , DOI

Sin referencias

Cargando información sobre las referencias
Mostrar resumen

OBJECTIVE:

Although osteoarthritis (OA) is considered a non-inflammatory condition, it is widely accepted that synovial inflammation is a feature of OA. However, the role of immune cells and their cytokines in OA is largely unknown. This narrative systematic review summarizes the knowledge of inflammatory properties, immune cells and their cytokines in synovial tissues (STs) of OA patients.

DESIGN:

Broad literature search in different databases was performed which resulted in 100 articles.

RESULTS:

Of 100 articles 33 solely investigated inflammation in OA ST with or without comparison with normal samples; the remaining primarily focussed on rheumatoid arthritis (RA) ST. Studies investigating different severity stages or cellular source of cytokines were sparse. OA ST displayed mild/moderate grade inflammation when investigated by means of haematoxylin and eosin (H&E) staining. Most frequently found cells types were macrophages, T cells and mast cells (MCs). Overall the number of cells was lower than in RA, although the number of MCs was as high as or sometimes even higher than in RA ST. Cytokines related to T cell or macrophage function were found in OA ST. Their expression was overall higher than in normal ST, but lower than in RA ST. Their cellular source remains largely unknown in OA ST.

CONCLUSION:

Inflammation is common in OA ST and characterized by immune cell infiltration and cytokine secretion. This inflammation seems quantitatively and qualitatively different from inflammation in RA. Further research is needed to clarify the role of inflammation, immune cells and their cytokines in the pathogenesis of OA.

Mostrar resumen

Revisión sistemática

No clasificado

Risk factors for progression in hand osteoarthritis: a systematic review.

Año 2013
Revista Arthritis care & research
Enlaces Pubmed , DOI

Este artículo incluye 17 Estudios primarios 17 Estudios primarios (17 referencias)

Cargando información sobre las referencias
Mostrar resumen

OBJECTIVE:

To assess the risk factors for progression of hand osteoarthritis (OA).

METHODS:

In a systematic review of cohort studies, medical literature databases were searched up to May 2012 for articles reporting data on the association between risk factors and hand OA progression. The quality of these studies was assessed by 2 independent reviewers using a criteria scoring system of 16 items, and studies were dichotomized into those with scores of 69% or over and those with scores under 69%. Best evidence synthesis was used to determine the level of evidence per risk factor.

RESULTS:

In total, 14 articles that fulfilled the selection criteria were included, of which 8 were high quality. The most frequently investigated risk factors were age, sex, radiographic features (e.g., erosive OA), and scintigraphy. Progression was mostly defined by radiographic criteria, but also clinical progression as an outcome was described. Most of the investigated risk factors showed limited or inconclusive evidence for an association with hand OA progression. Limited evidence according to the best evidence synthesis with most available studies was present for the association between a positive scintigraphic scan and radiographic progression (up to 2.8 times more progression than negative joints).

CONCLUSION:

Limited evidence is available for a positive association between an abnormal scintigraphic scan and radiographic hand OA progression. These data suggest that a positive scintigraphic scan as an inclusion criterion for studies that aim to show structural modification can increase the power of such studies. Future longitudinal studies with a well-defined baseline population are needed to search for risk factors of hand OA progression.

Mostrar resumen